Random Walk Imaging

Projects

Random Walk Imaging make use of diffusion MRI in order to provide new specific imaging biomarkers for secure diagnosis and treatment follow-up, without using contrast fluids and invasive biopsies.

Since this development demands a truly multidisciplinary effort, we work closely with well-renowned clinical researchers all over the world. Selected projects are found below.

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  • Diffusion Symposium 2018 at Grand Hôtel Mölle

    16th – 19th of January 2018 Free gradient waveforms, q-trajectories, and fat b-tensors The last few years have brought forward new and exciting NMR/MRI diffusion encoding schemes that goes beyond the pulsed gradient regime, and this symposium aims to bring together members of the academic community to discuss recent advances and challenges of these novel […]

    Microstructure differences in brain tumors

    This study purpose is to investigate how microscopic structure and variances in cell-density differs in brain tumors. A quick scan time protocol of 3 minutes is added to all current brain tumor investigations on the Siemens Prisma 3 T in Lund, Sweden. Initial results comprise mainly meningiomas and gliomas, where the results mirror previously reported […]

    Multiple sclerosis project

    Our colleague Dr. Samo Lasič, together with collaborators in Hvidovre, Denmark, run an ongoing study investigating whether our MRI methods are able to differentiate between MS-related pathologies in focal lesions, as well as in normal appearing white matter. They are also evaluating the diagnostic value of these new MRI methods, to prepare for implementation in […]

    Characterization of Epileptogenic Lesions by 7T MRI

    This project aims to explore how well 7 T diffusion MRI performs in characterizing epileptogenic lesions. Methods developed by Random Walk Imaging are added to an existing protocol, and the wish is to compare data to histology from excised tissue. Scan time is 7 minutes and is performed on a Philips Achieva (7 T, 60 […]

    Brain microstructure changes in Parkinson patients

    In this project, researchers are working with our methods to measure structure to investigate the magnitude of changes in brain microstructure of Parkinson patients, compared to healthy individuals. Scan time is 22 minutes and is performed on a Siemens Prisma 3 T. Initial results have shown promising results and will be further investigated once the […]

    Improved blood flow measurements

    In this study, it was demonstrated that our method to measure flow improves the accuracy and precision of the conventional imaging method. Also, the method developed by Random Walk Imaging is feasible for in vivo imaging of the brain perfusion fraction. Conventional imaging has a clinical interest with applications to tumors of the liver, breast, […]

    The link between tissue heterogeneity and diffusional variance can aid in distinguishing between aggressive and less aggressive brain tumors

    Non-invasive brain tumor differentiation

    In this article, our method to measure structure is used to non-invasively separate highly aggressive brain tumors from less aggressive ones. Microstructure of tumor tissue can be examined non-invasively using MRI. However, it is not well-established how differences in MRI measurements are coupled to tissue microstructure. To investigate how these two are linked, the following […]

    Breast cancer differentation with the RWI exchange method

    In this publication, different breast cancer subtypes are distinguished using our exchange method. Although MRI has shown promise for the characterization of breast cancer, it has low specificity to malignant subtypes. Here, the ability of our exchange method was tested, and shown to be able to distinguish different types of breast cancer cells. Furthermore, the […]