Diffusion MRI method to estimate director orientations

Our Research Partner, Prof. Daniel Topgaard has published an article in Physical Chemistry Chemical Physics, demonstrating the backbone of our methods – and why they can accomplish measurements inaccessible with conventional MRI.

The publication, Director orientations in lyotropic liquid crystals: diffusion MRI mapping of the Saupe order tensor, propose a novel diffusion MRI method that is able to better separate the different effects from the underlying tissue structure on the signal. The method is then tested in proof-of-concept experiments where the intricate patterns of the underlying structure is known, and the results of these show that the information obtained is done so at an unprecedented level of detail.

We find it very exciting that Prof. Topgaard believes this approach can be adapted to in vivo studies of tissue microstructure in normal and pathological tissues.

For the full article, please follow this link.

Random Walk Imaging AB is developing a novel proprietary approach to diffusion MRI. RWI is commercializing dVIEWR powered by MICE Toolkit™ as a novel software solution for clinical researchers and radiologists to better visualize and analyze diffusion MRI data. The company’s software solutions introduce a level of specificity to diffusion MRI that is unprecedented and that has the potential to non-invasively differentiate pathologies affected by changes in tissue microstructure. Based in Lund, part of the Swedish-Danish cross-border region of Medicon Valley, RWI has a broad intellectual property portfolio and unique translational expertise in advanced diffusion NMR and MRI methods.