Resolution limit of cylinder diameter estimation by diffusion MRI

Our colleague, Dr. Samo Lasič, and three of our Research Partners, Dr. Markus NilssonProf. Daniel Topgaard, and Prof. Carl-Fredrik Westin, have together with Dr. Ivana Drobnjak published their work on how to make novel diffusion encoding methods feasible in clinical settings, when aiming to accurately estimate smaller structures within the body.

Although diffusion MRI has been proposed to map axonal diameters non-invasively, in order to draw proper conclusions from your diffusion MRI data, you need to know your limits.  To accurately estimate small diameters, you need strong gradients – and clinical MRI scanners suffer from weaker gradients compared to preclinical scanners.

What is the resolution limit for standard clinical MRI scanners?  You need to look no further than here!

Random Walk Imaging AB is developing a novel proprietary approach to diffusion MRI. RWI is commercializing dVIEWR powered by MICE Toolkit™ as a novel software solution for clinical researchers and radiologists to better visualize and analyze diffusion MRI data. The company’s software solutions introduce a level of specificity to diffusion MRI that is unprecedented and that has the potential to non-invasively differentiate pathologies affected by changes in tissue microstructure. Based in Lund, part of the Swedish-Danish cross-border region of Medicon Valley, RWI has a broad intellectual property portfolio and unique translational expertise in advanced diffusion NMR and MRI methods.