Projects

Random Walk Imaging make use of diffusion MRI in order to provide new specific imaging biomarkers for secure diagnosis and treatment follow-up, without using contrast fluids and invasive biopsies.

Since this development demands a truly multidisciplinary effort, we work closely with well-renowned clinical researchers all over the world. Selected projects are found below.

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Microstructure differences in brain tumors

This study purpose is to investigate how microscopic structure and variances in cell-density differs in brain tumors. A quick scan time protocol of 3 minutes is added to all current brain tumor investigations on the Siemens Prisma 3 T in Lund, Sweden. Initial results comprise mainly meningiomas and gliomas, where the results mirror previously reported […]

Multiple sclerosis project

Our colleague Dr. Samo Lasič, together with collaborators in Hvidovre, Denmark, run an ongoing study investigating whether our MRI methods are able to differentiate between MS-related pathologies in focal lesions, as well as in normal appearing white matter. They are also evaluating the diagnostic value of these new MRI methods, to prepare for implementation in […]

Characterization of Epileptogenic Lesions by 7T MRI

This project aims to explore how well 7 T diffusion MRI performs in characterizing epileptogenic lesions. Methods developed by Random Walk Imaging are added to an existing protocol, and the wish is to compare data to histology from excised tissue. Scan time is 7 minutes and is performed on a Philips Achieva (7 T, 60 […]

Brain microstructure changes in Parkinson patients

In this project, researchers are working with our methods to measure structure to investigate the magnitude of changes in brain microstructure of Parkinson patients, compared to healthy individuals. Scan time is 22 minutes and is performed on a Siemens Prisma 3 T. Initial results have shown promising results and will be further investigated once the […]

The link between tissue heterogeneity and diffusional variance can aid in distinguishing between aggressive and less aggressive brain tumors

Non-invasive brain tumor differentiation

In this article, our method to measure structure is used to non-invasively separate highly aggressive brain tumors from less aggressive ones. Microstructure of tumor tissue can be examined non-invasively using MRI. However, it is not well-established how differences in MRI measurements are coupled to tissue microstructure. To investigate how these two are linked, the following […]

Brain plasticity and learning capabilities

Here, scientists investigate whether performance in auditory and visual statistical learning tasks are related to white matter microstructure. Acquired data will be compared with independent assessments of statistical learning capabilities. Scan time is 9 minutes and is performed on a Siemens Prisma 3 T. Parts of the results in this project has been published by […]